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Article

Adaptation of CD8 T cell responses to changing HIV-1 sequences in a cohort of HIV-1 infected individuals not selected for a certain HLA allele.

PloS one - 1 Jan 2013

Roider Julia, Kalteis Anna-Lena, Vollbrecht Thomas, Gloning Lisa, Stirner Renate, Henrich Nadja, Bogner Johannes R, Draenert Rika

Abstract excerpt

HIV evades CD8 T cell mediated pressure by viral escape mutations in targeted CD8 T cell epitopes. A viral escape mutation can lead to a decline of the respective CD8 T cell response. Our question was what happened after the decline of a CD8 T cell response and - in the case of viral escape - if...

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Source

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Identifiers

PMID: 24312453
DOI: 10.1371/journal.pone.0080045
PMCID: PMC3849264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24312453-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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