Article
[Selection of HIV escape mutants by CTL and adaptation of HIV to HLA class I].
Uirusu - 1 Dec 2009
Takiguchi Masafumi
Abstract excerpt
HIV-1-specific CTLs, which can kill HIV-1-infected cells, play an important role in control HIV-1 replication. There are growing evidences that they select HIV-1 escape mutations so that escape HIV-1 mutants become dominant in the donors. A recent study analyzing approximately 2800 HIV-1 infected individuals in 9 different cohorts demonstrated that HIV escape mutants accumulated in the cohorts, demonstrating...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
