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Article

Polymorphisms in TLR4 and TLR2 genes, cytokine production and survival in rural Ghana.

European journal of human genetics : EJHG - 1 Apr 2010

May Linda, van Bodegom David, Frölich Marijke, van Lieshout Lisette, Slagboom P Eline, Westendorp Rudi G J, Kuningas Maris

Abstract excerpt

Toll-like receptors (TLRs) are involved in the induction of an adequate immune response on infection. We hypothesized that genetic variation in TLR4 and TLR2 genes could influence this response and lead to variability in cytokine production and survival. We tested this hypothesis in 4292 particip...

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Source

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Identifiers

PMID: 19844258
DOI: 10.1038/ejhg.2009.182
PMCID: PMC2987239

Genes

TLR4
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19844258-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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