Article
Association of interleukin-33 gene polymorphisms with susceptibility to Plasmodium falciparum infection.
Malaria journal - 11 Jun 2026
Aljarba Nada H, Alghnnam Fatimah, Al-Qahtani Arwa A, Al-Hazani Tahani Mohamed, Al Marzan Abdullah, Bohol Marie Fe F, Alhamlan Fatimah, Shafeai Mohammed I, Rudiny Fuad H, Motaen Ali M, Alkahtani Saad, Al-Qahtani Ahmed A
Abstract excerpt
BACKGROUND: Host immune genetic variation contributes to inter-individual differences in susceptibility to Plasmodium falciparum malaria and parasite-burden response. Interleukin-33 (IL-33), an IL-1 family alarmin signaling through ST2, regulates innate and adaptive immune responses during infection. Although IL-33/ST2 signaling has been implicated in malaria-related immune regulation, the contribution of IL-33...
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