Article
CLU genetic variants and cognitive decline among elderly and oldest old.
PloS one - 1 Jan 2013
Mengel-From Jonas, Thinggaard Mikael, Lindahl-Jacobsen Rune, McGue Matt, Christensen Kaare, Christiansen Lene
Abstract excerpt
The CLU gene is one of the prime genetic candidates associated with Alzheimers disease. In the present study CLU genotypes and haplotypes were associated with baseline cognition and the rate of cognitive decline in two cohorts, the Danish 1905 birth cohort (93 years of age in 1998) and the Longitudinal Study of Aging Danish twins (LSADT) (73-83 year old twins in 1997). Both Mini Mental State Examination (MMSE)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
