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Article

MTHFR polymorphisms and cognitive ageing in the ninth decade: the Lothian Birth Cohort 1921.

Genes, brain, and behavior - 1 Apr 2011

Schiepers O J G, van Boxtel M P J, Harris S E, Gow A J, Pattie A, Brett C E, de Groot R H M, Jolles J, Starr J M, Deary I J

Abstract excerpt

Low blood levels of B vitamins have been implicated in age-associated cognitive impairment. The present study investigated the association between genetic variation in folate metabolism and age-related cognitive decline in the ninth decade of life. Both the 677C>T (rs1801133) polymorphism and the scarcely studied 1298A>C (rs1801131) polymorphism of the MTHFR gene were assessed in relation to cognitive change over...

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Source

Identifiers

PMID: 21255267
DOI: 10.1111/j.1601-183X.2010.00675.x

Genes

MTHFR
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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