Article
Association of MTHFR and PICALM polymorphisms with Alzheimer's disease.
Molecular biology reports - 1 Mar 2015
Belcavello Luciano, Camporez Daniela, Almeida Leila D, Morelato Renato L, Batitucci Maria C P, de Paula Flavia
Abstract excerpt
Alzheimer's disease (AD) is a complex neurodegenerative disorder and the primary cause of dementia in the elderly and causes a decrease in cognition, functionality, and behaviour. Genetic risk factors play an important role in the pathogenesis of AD. In this case-control study, we aimed to investigate whether single nucleotide polymorphisms in MTHFR (rs1801133), PICALM (3851719), CLU (rs11136000), and CR1...
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