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Article

Recombinogenic conditions influence partner choice in spontaneous mitotic recombination.

PLoS genetics - 1 Nov 2013

Cauwood James D, Johnson Anthony L, Widger Alexander, Cha Rita S

Abstract excerpt

Mammalian common fragile sites are loci of frequent chromosome breakage and putative recombination hotspots. Here, we utilized Replication Slow Zones (RSZs), a budding yeast homolog of the mammalian common fragile sites, to examine recombination activities at these loci. We found that rates of URA3 inactivation of a hisG-URA3-hisG reporter at RSZ and non-RSZ loci were comparable under all conditions tested,...

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Share to Chromosome Breakage
Share to Chromosome Fragile Sites
Share to DNA Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Recombination, Genetic

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Source

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Identifiers

PMID: 24244194
DOI: 10.1371/journal.pgen.1003931
PMCID: PMC3820797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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