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Article

Mammalian meiotic recombination hot spots.

Annual review of genetics - 1 Jan 2007

Arnheim Norman, Calabrese Peter, Tiemann-Boege Irene

Abstract excerpt

Our understanding of the details of mammalian meiotic recombination has recently advanced significantly. Sperm typing technologies, linkage studies, and computational inferences from population genetic data have together provided information in unprecedented detail about the location and activity of the sites of crossing-over in mice and humans. The results show that the vast majority of meiotic recombination...

Topics

Alleles
Animals
DNA
Gene Conversion
Humans
Male
Meiosis
Polymorphism, Genetic
Recombination, Genetic
Spermatozoa

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 18076329
DOI: 10.1146/annurev.genet.41.110306.130301

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