Article
Mammalian recombination hot spots: properties, control and evolution.
Nature reviews. Genetics - 1 Mar 2010
Paigen Kenneth, Petkov Petko
Abstract excerpt
Recombination, together with mutation, generates the raw material of evolution, is essential for reproduction and lies at the heart of all genetic analysis. Recent advances in our ability to construct genome-scale, high-resolution recombination maps and new molecular techniques for analysing recombination products have substantially furthered our understanding of this important biological phenomenon in humans and...
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