Article
The Red Queen theory of recombination hotspots.
Journal of evolutionary biology - 1 Mar 2011
Ubeda F, Wilkins J F
Abstract excerpt
Recombination hotspots are small chromosomal regions, where meiotic crossover events happen with high frequency. Recombination is initiated by a double-strand break (DSB) that requires the intervention of the molecular repair mechanism. The DSB repair mechanism may result in the exchange of homologous chromosomes (crossover) and the conversion of the allelic sequence that breaks into the one that does not break...
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