Article
Statistical testing of shared genetic control for potentially related traits.
Genetic epidemiology - 1 Dec 2013
Wallace Chris
Abstract excerpt
Integration of data from genome-wide single nucleotide polymorphism (SNP) association studies of different traits should allow researchers to disentangle the genetics of potentially related traits within individually associated regions. Formal statistical colocalisation testing of individual regions requires selection of a set of SNPs summarising the association in a region. We show that the SNP selection method...
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