Article

Statistical Colocalization of Genetic Risk Variants for Related Autoimmune Diseases in the Context of Common Controls

2015-06-08

Abstract excerpt

Identifying whether potential causal variants for related diseases are shared can increase understanding of the shared etiology between diseases. Colocalization methods are designed to disentangle shared and distinct causal variants in regions where two diseases show association, but existing methods are limited by assuming independent datasets. We extended existing methods to allow for the shared control design c...

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Literature Corpus work: 90f2e9b7-7ee2-56de-8534-7216a47e56f5
DOI: 10.1101/020651

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