Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gr1intCD11b+ Myeloid-Derived Suppressor Cells in Mycobacterium tuberculosis Infection

1 Nov 2013

Abstract excerpt

BACKGROUND: Tuberculosis is one of the world's leading killers, stealing 1.4 million lives and causing 8.7 million new and relapsed infections in 2011. The only vaccine against tuberculosis is BCG which demonstrates variable efficacy in adults worldwide. Human infection with Mycobacterium tuberculosis results in the influx of inflammatory cells to the lung in an attempt to wall off bacilli by forming a granuloma....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune cells in cancer
Share to Immune Response and Inflammation
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24224058
DOI: 10.1371/journal.pone.0080669

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gr1intCD11b+ Myeloid-Derived Suppressor Cells in Mycobacterium tuberculosis InfectionPMID 24224058Read ↗

iNOS-producing inflammatory dendritic cells constitute the major infected cell type during the chronic Leishmania major infection phase of C57BL/6 resistant mice.Semantic proximity Read ↗

Recently activated CD4 T cells in tuberculosis express OX40 as a target for host-directed immunotherapySemantic proximity Read ↗

Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.Semantic proximity Read ↗

Myeloid arginase-1 controls excessive inflammation and modulates T cell responses in Pseudomonas aeruginosa pneumonia.Semantic proximity Read ↗

Neutrophil subsets play dual roles in tuberculosis by producing inflammasome dependent-IL-1β or suppressing T-cells via PD-L1Semantic proximity Read ↗

MDSC depletion during immunization with heat-killed <i>Mycobacterium tuberculosis</i> increases protection against BCG infectionSemantic proximity Read ↗

Type I IFN signaling in the absence of IRGM1 promotes M. tuberculosis replication in immune cells by suppressing T cell responsesSemantic proximity Read ↗

Neutrophils reprograms the bone marrow to impair T-cell immunity during tuberculosisSemantic proximity Read ↗

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity.Semantic proximity Read ↗

Multiomic analysis identifies suppressive myeloid cell populations in human TB granulomasSemantic proximity Read ↗

<i>Mycobacterium tuberculosis</i> ‐specific CD8 <sup>+</sup> T cells are functionally and phenotypically different between latent infection and active diseaseSemantic proximity Read ↗

Type I IFN signaling triggers immunopathology in tuberculosis‐susceptible mice by modulating lung phagocyte dynamicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.