Article

Neutrophils reprograms the bone marrow to impair T-cell immunity during tuberculosis

2022-06-29

Abstract excerpt

<h4>ABSTRACT</h4> Mycobacterium tuberculosis (Mtb) infection induces persistent influx of neutrophils that associates with poor bacterial control and clinical outcome from tuberculosis (TB). Although implicated in TB pathology, the mechanism by which these cells contribute to pathogenesis is poorly understood. Using Cell-DIVE multiplexed immunofluorescence imaging and spatial analysis of inflammatory TB lesions,...

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Literature Corpus work: ba140d84-93e7-585a-af84-067382afd620
DOI: 10.1101/2022.06.28.498035

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