Article

Multiomic analysis identifies suppressive myeloid cell populations in human TB granulomas

2025-03-13

Abstract excerpt

Tuberculosis (TB) remains a major global health challenge, particularly in the context of multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb). Host-directed therapies (HDTs) have been proposed as adjunctive therapy to enhance immune control of infection. Recently, one such HDT, pharmacologic modulation of myeloid-derived suppressor cells (MDSCs), has been proposed to treat MDR-TB. While MDSCs have been wel...

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Literature Corpus work: 31c028b0-e461-55a5-9fe7-4c0854befcc4
DOI: 10.1101/2025.03.10.642376

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