Article
A pharmaco-epistasis strategy reveals a new cell size controlling pathway in yeast.
Molecular systems biology - 12 Nov 2013
Moretto Fabien, Sagot Isabelle, Daignan-Fornier Bertrand, Pinson Benoît
Abstract excerpt
Cell size is a complex quantitative trait resulting from interactions between intricate genetic networks and environmental conditions. Here, taking advantage of previous studies that uncovered hundreds of genes affecting budding yeast cell size homeostasis, we performed a wide pharmaco-epistasis analysis using drugs mimicking cell size mutations. Simple epistasis relationship emerging from this approach allowed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
