Article

Small effect-size mutations cumulatively affect yeast quantitative traits

2017-04-11

Abstract excerpt

<h4>Summary</h4> Quantitative traits are influenced by pathways that have traditionally been defined through genes that have a large loss- or gain-of-function effect. However, in theory, a large number of small effect-size genes could cumulative play a substantial role in pathway function, potentially by acting as “modifiers” that tune the levels of large effect size pathway components. To understand the role of...

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Literature Corpus work: f2ef18ee-f885-5961-9517-55a47be3f062
DOI: 10.1101/126409

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