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Article

The Natural Product Resveratrol Inhibits Yeast Cell Separation by Extensively Modulating the Transcriptional Landscape and Reprogramming the Intracellular Metabolome.

PloS one - 1 Jan 2016

Wang Zhe, Gu Zhongkai, Shen Yan, Wang Yang, Li Jing, Lv Hong, Huo Keke

Abstract excerpt

An increasing number of studies have shown that the promising compound resveratrol treats multiple diseases, such as cancer and aging; however, the resveratrol mode-of-action (MoA) remains largely unknown. Here, by virtue of multiple omics approaches, we adopted fission yeast as a model system with the goal of dissecting the common MoA of the anti-proliferative activity of resveratrol. We found that the...

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Identifiers

PMID: 26950930
DOI: 10.1371/journal.pone.0150156
PMCID: PMC4780762

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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