Article
Dynamic changes in viral population structure and compartmentalization during chronic hepatitis C virus infection in children.
Virology - 1 Dec 2013
Gismondi María Inés, Díaz Carrasco Juan María, Valva Pamela, Becker Pablo Daniel, Guzmán Carlos Alberto, Campos Rodolfo Héctor, Preciado María Victoria
Abstract excerpt
Classic phylogenetic and modern population-based clustering methods were used to analyze hepatitis C virus (HCV) evolution in plasma and to assess viral compartmentalization within peripheral blood mononuclear cells (PBMCs) in 6 children during 3.2-9.6yr of follow-up. Population structure analysis of cloned amplicons encompassing hypervariable region 1 led to the distinction of two evolutionary patterns, one...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
