Article
Inter and intrapatient evolution of hepatitis C virus.
Annals of hepatology - 1 Jan 2000
Di Lello Federico A, Culasso Andrés C A, Campos Rodolfo H
Abstract excerpt
Hepatitis C virus (HCV) has a short replication time, high mutation rates and large population sizes, all of which make it an excellent experimental model for evolution studies, because evolution can be visualized in real-time. In this review, we discuss the implications to study HCV evolution at the interpatient and intrapatient levels of infection. The HCV interpatient dynamics is relatively slow, because the...
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