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Article

Evidence of distinct populations of hepatitis C virus in the liver and plasma of patients co-infected with HIV and HCV.

Journal of medical virology - 1 Aug 2014

Blackard Jason T, Ma Gang, Sengupta Satarupa, Martin Christina M, Powell Eleanor A, Shata M Tarek, Sherman Kenneth E

Abstract excerpt

Viral diversity is an important predictor of hepatitis C virus (HCV) treatment response and may influence viral pathogenesis. HIV influences HCV variability in the plasma; however, limited data on viral variability are available from distinct tissue/cell compartments in patients co-infected with HIV and HCV. Thus, this exploratory study evaluated diversity of the hypervariable region 1 (HVR1) of HCV in the plasma...

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Identifiers

PMID: 24788693
DOI: 10.1002/jmv.23968
PMCID: PMC4562016

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