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Article

Analysis of a non-structural gene reveals evidence of possible hepatitis C virus (HCV) compartmentalization.

Journal of medical virology - 1 Feb 2012

Blackard Jason T, Ma Gang, Welge Jeffrey A, Martin Christina M, Sherman Kenneth E, Taylor Lynn E, Mayer Kenneth H, Jamieson Denise J

Abstract excerpt

Viral diversity is a hallmark of hepatitis C virus (HCV) infection; however, only limited data are available regarding HCV variability in extrahepatic sites, and none have systematically compared diversity in non-structural and structural genomic regions. Therefore, HCV diversity in the NS5B and envelope 1 (E1) hypervariable region 1 (HVR1) genes was evaluated in matched sera and peripheral blood mononuclear...

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Share to Hepacivirus
Share to Hepatitis C, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocytes, Mononuclear

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Share to Sequence Analysis, Protein

Share to Viral Envelope Proteins

Share to Viral Nonstructural Proteins

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Source

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Identifiers

PMID: 22170544
DOI: 10.1002/jmv.22269
PMCID: PMC3243959

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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