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Article

Frequent compartmentalization of hepatitis C virus variants in circulating B cells and monocytes.

Hepatology (Baltimore, Md.) - 1 Mar 2004

Ducoulombier Delphine, Roque-Afonso Anne-Marie, Di Liberto Gaëtana, Penin François, Kara Rachid, Richard Yolande, Dussaix Elisabeth, Féray Cyrille

Abstract excerpt

Differences in the composition of the hepatitis C virus (HCV) quasispecies between plasma and blood mononuclear cells (BMC) strongly suggest that BMCs support viral replication. We examined the frequency of such compartmentalization, the cell types involved, the constraints exerted on the different variants, and the role of immunoglobulin-complexed variants. We screened the hypervariable region (HVR1) of HCV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14999702
DOI: 10.1002/hep.20087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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