Article
Evolution of hepatitis C virus quasispecies in children with chronic hepatitis C.
Infection - 1 Apr 2006
Gerotto M, Resti M, Dal Pero F, Migliorato I, Alberti A, Bortolotti F
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) circulates as a mixture of different but closely related genomes: this quasispecies nature could be essential for virus persistence and could induce resistance to interferon therapy. Since little is known on the behavior of HCV quasispecies in children and adolescents with chronic hepatitis C, we analyzed the virus population in six untreated children during a 5-year follow-up....
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