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Article

The surface molecular signature of leukemic cells is associated with NPM1 mutations and FLT3 -ITD in patients with de novo acute myeloid leukemia.

Acta haematologica - 1 Jan 2014

Su Long, Gao Su-Jun, Li Wei, Tan Ye-Hui, Cui Jiu-Wei, Han Wei

Abstract excerpt

Certain molecular mutations are associated with signs of cell morphology and differentiation in acute myeloid leukemia (AML). However, only limited data are available for the detailed analysis of such correlations. In this study, AML patients were classified into 4 subsets according to CD34, HLA-DR and CD11c expression levels. Significantly low CD34 antigen expression was observed in nucleophosmin (NPM1)-mutated...

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Topics

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Share to Antigens, CD34
Share to CD11c Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to fms-Like Tyrosine Kinase 3

Share to HLA-DR Antigens

Share to Immunophenotyping

Share to Leukemia, Myeloid, Acute

Share to Nucleophosmin

Share to Tandem Repeat Sequences

Source

Identifiers

PMID: 24192815
DOI: 10.1159/000353663

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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