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Article

CD34 expression predicts an adverse outcome in patients with NPM1-positive acute myeloid leukemia.

Human pathology - 1 Oct 2013

Dang Harry, Chen Yan, Kamel-Reid Suzanne, Brandwein Joseph, Chang Hong

Abstract excerpt

Patients with acute myeloid leukemia (AML) harboring an NPM1 mutation exhibit a heterogeneous clinical outcome. Recent studies have shown that the absence of FLT3 internal tandem duplication (FLT3-ITD) mutation confers a favorable prognosis in NPM1-positive AML. However, the prognostic impact of immunophenotypes in this subgroup remains unclear. In this study, FLT3 mutation status and immunophenotypic profile of...

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Source

Identifiers

PMID: 23701943
DOI: 10.1016/j.humpath.2013.03.007

Genes

FLT3
NPM1
EFS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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