Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The correlation of next-generation sequencing-based genotypic profiles with clinicopathologic characteristics in NPM1-mutated acute myeloid leukemia.

BMC cancer - 8 Jul 2021

Wang Biao, Yang Bin, Wu Wei, Liu Xuan, Li Haiqian

Abstract excerpt

The purpose of this study was to analyze the association between next-generation sequencing (NGS) genotypic profiles and conventional clinicopathologic characteristics in patients with acute myeloid leukemia (AML) with NPM1 mutation (NPM1mut). We selected 238 NPM1mut patients with available NGS information on 112 genes related to blood diseases using the χ2 and Mann-Whitney U tests and a multivariable logistic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Nuclear Proteins

Share to Nucleophosmin

Source

Open in PubMed Open full text

Identifiers

PMID: 34238278
DOI: 10.1186/s12885-021-08455-7
PMCID: PMC8268444

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The correlation of next-generation sequencing-based genotypic profiles with clinicopathologic characteristics in NPM1-mutated acute myeloid leukemia.PMID 34238278Read ↗

Correlation of Next-Generation Sequencing Based Genotypic Profiles with MICM Characteristics in NPM1 Mutated Acute Myeloid LeukemiaSemantic proximity Read ↗

[Association of Next Generation Sequencing Based Genotypic Profiling with MICM Characteristics in NPM1 Mutated Acute Myeloid Leukemia].Semantic proximity Read ↗

Clinical prognostic value of different NPM1 mutations in acute myeloid leukemia patients.Semantic proximity Read ↗

Cytogenetic abnormalities in NPM1-mutated acute myeloid leukemia.Semantic proximity Read ↗

Genetic biomarkers identify a subgroup of high-risk patients within low-risk NPM1-mutated acute myeloid leukemia.Semantic proximity Read ↗

The clinicopathologic significance of NPM1 mutation and ability to detect mutated NPM1 by immunohistochemistry in non-AML myeloid neoplasms.Semantic proximity Read ↗

Acute Myeloid Leukaemia with Normal Cytogenetics and NPM1-Mutation: Impact of Mutation Topography on OutcomesSemantic proximity Read ↗

[Using next generation sequencing technology to analyze gene mutations in patients with acute myeloid leukemia and the impact on prognosis].Semantic proximity Read ↗

Correlation of NPM1 immunohistochemistry with mutation subtypes, clinicopathologic variables and molecular testing in AML with NPM1 mutation.Semantic proximity Read ↗

[The immunophenotypic and clinical characteristics of NPM1 mutated acute myeloid leukemia patients].Semantic proximity Read ↗

High NPM1-mutant allele burden at diagnosis predicts unfavorable outcomes in de novo AML.Semantic proximity Read ↗

Next-generation sequencing reveals gene mutations landscape and clonal evolution in patients with acute myeloid leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.