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Article

Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1).

Blood - 6 May 2010

Falini Brunangelo, Macijewski Katja, Weiss Tamara, Bacher Ulrike, Schnittger Susanne, Kern Wolfgang, Kohlmann Alexander, Klein Hans-Ulrich, Vignetti Marco, Piciocchi Alfonso, Fazi Paola, Martelli Maria Paola, Vitale Antonella, Pileri Stefano, Miesner Miriam, Santucci Antonella, Haferlach Claudia, Mandelli Franco, Haferlach Torsten

Abstract excerpt

NPM1-mutated acute myeloid leukemia (AML) is a provisional entity in the 2008 World Health Organization (WHO) classification of myeloid neoplasms. The significance of multilineage dysplasia (MLD) in NPM1-mutated AML is unclear. Thus, in the 2008 WHO classification, NPM1-mutated AML with MLD is classified as AML with myelodysplasia (MD)-related changes (MRCs). We evaluated morphologically 318 NPM1-mutated AML...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20203266
DOI: 10.1182/blood-2009-08-240457

Genes

NPM1
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1).PMID 20203266Read ↗

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