Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?

Blood - 27 Jan 2011

Falini Brunangelo, Martelli Maria Paola, Bolli Niccolò, Sportoletti Paolo, Liso Arcangelo, Tiacci Enrico, Haferlach Torsten

Abstract excerpt

After the discovery of NPM1-mutated acute myeloid leukemia (AML) in 2005 and its subsequent inclusion as a provisional entity in the 2008 World Health Organization classification of myeloid neoplasms, several controversial issues remained to be clarified. It was unclear whether the NPM1 mutation was a primary genetic lesion and whether additional chromosomal aberrations and multilineage dysplasia had any impact...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Founder Effect
Share to Leukemia, Myeloid, Acute

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Biological

Share to Mutant Proteins

Share to Mutation

Share to Nuclear Proteins

Share to Nucleophosmin

Share to Prognosis

Source

Identifiers

PMID: 21030560
DOI: 10.1182/blood-2010-08-299990

Genes

NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?PMID 21030560Read ↗

Genetic, Phenotypic, and Clinical Heterogeneity of NPM1-Mutant Acute Myeloid LeukemiasSemantic proximity Read ↗

Nucleophosmin (NPM1) mutations in adult and childhood acute myeloid leukaemia: towards definition of a new leukaemia entity.Semantic proximity Read ↗

NPM1-Mutated Acute Myeloid Leukemia: Recent Developments and Open Questions.Semantic proximity Read ↗

Genetic. Phenotypic and Clinical Heterogeneity of NPM1-Mutant Acute Myeloid LeukemiasSemantic proximity Read ↗

Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives.Semantic proximity Read ↗

NPM1-mutated acute myeloid leukemia: from bench to bedside.Semantic proximity Read ↗

NPM1 mutations and cytoplasmic nucleophosmin are mutually exclusive of recurrent genetic abnormalities: a comparative analysis of 2562 patients with acute myeloid leukemiaSemantic proximity Read ↗

Diagnostic and therapeutic pitfalls in NPM1-mutated AML: notes from the field.Semantic proximity Read ↗

Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1).Semantic proximity Read ↗

Acute myeloid leukemia with mutated nucleophosmin (NPM1): molecular, pathological, and clinical features.Semantic proximity Read ↗

Nucleophosmin1 (NPM1) abnormality in hematologic malignancies, and therapeutic targeting of mutant NPM1 in acute myeloid leukemiaSemantic proximity Read ↗

Nucleophosmin mutation in de-novo acute myeloid leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.