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Article

Mutation of NPM1 and FLT3 genes in acute myeloid leukemia and their association with clinical and immunophenotypic features.

Disease markers - 1 Jan 2013

Chauhan Pradeep Singh, Ihsan Rakhshan, Singh L C, Gupta Dipendra Kumar, Mittal Vishakha, Kapur Sujala

Abstract excerpt

BACKGROUND: Mutations in NPM1 and FLT3 genes represent the most frequent genetic alterations and important diagnostic and prognostic indicators in patients with acute myeloid leukemia (AML). OBJECTIVE: We investigated the prevalence and clinical characteristics of NPM1 and FLT3 mutations in 161 patients of de novo AML including adults and children. RESULTS: NPM1 mutation was found in 21% and FLT3 mutation in 25%...

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Source

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Identifiers

PMID: 24288427
DOI: 10.1155/2013/582569
PMCID: PMC3830788

Genes

NPM1
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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