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Variable copy number of mitochondrial DNA (mtDNA) predicts worse prognosis in advanced gastric cancer patients

21 Oct 2013

Abstract excerpt

BACKGROUND: Change of mitochondrial DNA (mtDNA) copy number is widely reported in various human cancers, including gastric cancer, and is considered to be an important hallmark of cancers. However, there is remarkably little consensus on the value of variable mtDNA content in the prognostic evaluation of this cancer. METHODS: Using real-time quantitative PCR approach, we examined mtDNA copy number in a cohort of...

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PMID: 24144008
DOI: 10.1186/1746-1596-8-173

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