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Article

Association of decreased mitochondrial DNA content with the progression of colorectal cancer

12 Mar 2013

Abstract excerpt

BACKGROUND: Experimental data suggest that mitochondria is involved in tumorigenesis. However, little is known about the qualitative and quantitative changes of mtDNA in colorectal cancer tissues. We therefore conducted possible correlations of the mitochondrial DNA (mtDNA) copy number in colorectal cancer (CRC) with clinical and pathological findings and CRC prognosis. METHODS: mtDNA copy numbers in CRC cancer...

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PMID: 23497023
DOI: 10.1186/1471-2407-13-110

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