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Article

Mitochondrial DNA alterations in the progression of gastric carcinomas: unexplored issues and future research needs.

World journal of gastroenterology - 21 Nov 2014

Rigoli Luciana, Caruso Rosario Alberto

Abstract excerpt

Gastric cancer is the second most frequent cause of cancer death worldwide. Patients infected with Helicobacter pylori (H. pylori) are at increased risk of gastric cancer. H. pylori induces genomic instability in both nuclear and mitochondrial (mt) DNA of gastric epithelial cells. Changes in mtDNA represent an early event during gastric tumorigenesis, and thus may serve as potential biomarkers for early detection...

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Identifiers

PMID: 25473169
DOI: 10.3748/wjg.v20.i43.16159
PMCID: PMC4239503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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