Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic Changes of Mitochondrial DNA Copy Number in Gastrointestinal Tract Cancers: A Systematic Review and Meta-Analysis.

Cancer investigation - 1 Feb 2021

Alikhani Mehdi, Touati Eliette, Karimipoor Morteza, Vosough Massoud, Eybpoosh Sana, Mohammadi Marjan

Abstract excerpt

We have performed a systematic review and meta-analysis for evaluation of mitochondrial DNA copy number (mtDNA-CN) alterations in peripheral blood leukocytes (PBL), and tumor tissues of gastrointestinal tract (GIT) cancers. Analysis of the PBL demonstrated a significant decrease [OR: 0.6 (0.5, 0.8)] and increase [OR: 1.4 (1.1, 1.9)] prior to and following GIT cancer development, respectively. This trend was more...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Copy Number Variations
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Early Detection of Cancer

Share to Gastrointestinal Neoplasms

Share to Genetic Predisposition to Disease

Share to Leukocytes, Mononuclear

Share to Mitochondria

Source

Identifiers

PMID: 33290105
DOI: 10.1080/07357907.2020.1857394

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic Changes of Mitochondrial DNA Copy Number in Gastrointestinal Tract Cancers: A Systematic Review and Meta-Analysis.PMID 33290105Read ↗

Mitochondrial DNA copy number and risk of gastric cancer: a report from the Shanghai Women's Health Study.Semantic proximity Read ↗

Mitochondrial Copy Number is Associated with Colorectal Cancer RiskSemantic proximity Read ↗

Association between mitochondrial DNA content in leukocytes and colorectal cancer riskSemantic proximity Read ↗

Generation, function and diagnostic value of mitochondrial DNA copy number alterations in human cancers.Semantic proximity Read ↗

Association of decreased mitochondrial DNA content with the progression of colorectal cancerSemantic proximity Read ↗

Mitochondrial genome instability and mtDNA depletion in human cancers.Semantic proximity Read ↗

Pre-diagnostic leukocyte mitochondrial DNA copy number and colorectal cancer riskSemantic proximity Read ↗

Association of Leukocyte Mitochondrial DNA Copy Number with Colorectal Cancer Risk: Results from the Shanghai Women's Health StudySemantic proximity Read ↗

Pan-cancer analysis reveals mtDNA copy number as a key determinant of mutational load and disease progression in cancerSemantic proximity Read ↗

Mitochondrial DNA copy number in colorectal cancer: between tissue comparisons, clinicopathological characteristics and survivalSemantic proximity Read ↗

Uncovering the profile of somatic mtDNA mutations in Chinese colorectal cancer patients.Semantic proximity Read ↗

Somatic mutations of mitochondrial DNA in digestive tract cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.