Article
On the effects of malaria treatment on parasite drug resistance--probability modelling of genotyped malaria infections.
The international journal of biostatistics - 12 Oct 2013
Kum Cletus Kwa, Thorburn Daniel, Ghilagaber Gebrenegus, Gil Pedro, Björkman Anders
Abstract excerpt
We compare the frequency of resistant genes of malaria parasites before treatment and at first malaria incidence after treatment. The data come from a clinical trial at two health facilities in Tanzania and concerns single nucleotide polymorphisms (SNPs) at three positions believed to be related to resistance to malaria treatment. A problem is that mixed infections are common, which both obscures the underlying...
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