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Article

Modelling the development of resistance of Plasmodium falciparum to anti-malarial drugs.

Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Jan 2000

Cross A P, Singer B

Abstract excerpt

A hybrid transmission/genetics model for the development of resistance by Plasmodium falciparum to anti-malarial drugs is set forth. Field data on pyrimethamine resistance are used to calibrate and test the model. Simulated consequences of different drug dosage and population coverage strategies are presented to illustrate an ethical dilemma. A strategy of maximally effective treatment for all infected...

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Identifiers

PMID: 1683034
DOI: 10.1016/0035-9203(91)90286-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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