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Article

Intensity of transmission and spread of gene mutations linked to chloroquine and sulphadoxine-pyrimethamine resistance in falciparum malaria.

International journal for parasitology - 15 Sept 2003

Talisuna Ambrose O, Langi Peter, Mutabingwa Theonest K, Van Marck Eric, Speybroeck Niko, Egwang Thomas G, Watkins William W, Hastings Ian M, D'Alessandro Umberto

Abstract excerpt

The number of malaria parasite clones per infection-multiplicity of parasite clones-is affected by the transmission intensity, multiplicity increases with increasing transmission. This affects the frequency of parasites' sexual recombination and, if several mutations in different genes are involved, can break down drug resistant genotypes. Therefore, the effects of malaria transmission intensity on the spread of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 13129527
DOI: 10.1016/s0020-7519(03)00156-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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