Article
Malaria haplotype frequency estimation.
Statistics in medicine - 20 Sept 2013
Wigger Leonore, Vogt Julia E, Roth Volker
Abstract excerpt
We present a Bayesian approach for estimating the relative frequencies of multi-single nucleotide polymorphism (SNP) haplotypes in populations of the malaria parasite Plasmodium falciparum by using microarray SNP data from human blood samples. Each sample comes from a malaria patient and contains one or several parasite clones that may genetically differ. Samples containing multiple parasite clones with different...
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