Article
The influence of drug treatment on the maintenance of schistosome genetic diversity.
Journal of mathematical biology - 1 Jul 2001
Feng Z, Curtis J, Minchella D J
Abstract excerpt
Drug treatment of patients with schistosomiasis may select for drug-resistant parasites. In this article, we formulate a deterministic model with multiple strains of schistosomes (helminth parasites with a two-host life cycles) in order to explore the role of drug treatment in the maintenance of a polymorphism of parasite strains that differ in their resistance levels. The basic reproductive numbers for all...
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