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Article

A spatio-temporal model of multi-marker antimalarial resistance.

Journal of the Royal Society, Interface - 1 Jan 2024

Foo Yong See, Flegg Jennifer A

Abstract excerpt

The emergence and spread of drug-resistant Plasmodium falciparum parasites have hindered efforts to eliminate malaria. Monitoring the spread of drug resistance is vital, as drug resistance can lead to widespread treatment failure. We develop a Bayesian model to produce spatio-temporal maps that depict the spread of drug resistance, and apply our methods for the antimalarial sulfadoxine-pyrimethamine. We infer...

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Identifiers

PMID: 38228183
DOI: 10.1098/rsif.2023.0570
PMCID: PMC10791536

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