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Article

TAF-4 is required for the life extension of isp-1, clk-1 and tpk-1 Mit mutants.

Aging - 1 Oct 2013

Khan Maruf H, Ligon Melissa, Hussey Lauren R, Hufnal Bryce, Farber Robert, Munkácsy Erin, Rodriguez Amanda, Dillow Andy, Kahlig Erynn, Rea Shane L

Abstract excerpt

While numerous life-extending manipulations have been discovered in the nematode Caenorhabditis elegans, one that remains most enigmatic is disruption of oxidative phosphorylation. In order to unravel how such an ostensibly deleterious manipulation can extend lifespan, we sought to identify the ensemble of nuclear transcription factors that are activated in response to defective mitochondrial electron transport...

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Source

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Identifiers

PMID: 24107417
DOI: 10.18632/aging.100604
PMCID: PMC3838777

Genes

CRH
JUN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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