Article
Impact of genetic polymorphisms in base excision repair genes on the risk of breast cancer in a Korean population.
Gene - 15 Dec 2013
Kim Kyoung-Yeon, Han Wonshik, Noh Dong-Young, Kang Daehee, Kwack Kyubum
Abstract excerpt
The contribution of single nucleotide polymorphisms (SNPs) in base excision repair (BER) genes to the risk of breast cancer (BC) was evaluated by focusing on two key genes: apurinic/apyrimidinic endonuclease 1 (APEX1) and 8-oxoguanine DNA glycosylase (OGG1). Genetic variations in the genes encoding these DNA repair enzymes may alter their functions and increase susceptibility to carcinogenesis. The aim of this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
