Article
Association of APEX1 and OGG1 gene polymorphisms with breast cancer risk among Han women in the Gansu Province of China.
BMC medical genetics - 2 May 2018
Wang Tao, Wang Haitao, Yang Suisheng, Guo Hongyun, Zhang Binming, Guo Huan, Wang Lan, Zhu Gongjian, Zhang Yongdong, Zhou Haihong, Zhang Xiuli, Li Haining, Su Haixiang
Abstract excerpt
BACKGROUND: Genetic variations in key DNA repair genes may influence DNA repair capacity, DNA damage and breast carcinogenesis. The current study aimed to estimate the association of APEX1 and OGG1 polymorphisms with the risk of breast cancer development. METHODS: A total of 518 patients with histopathologically confirmed breast cancer and 921 region- and age-matched cancer-free controls were genotyped for the...
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