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Article

Association between OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and breast cancer risk: a meta-analysis.

Diagnostic pathology - 3 Jun 2014

Peng Qiliu, Lu Yu, Lao Xianjun, Chen Zhiping, Li Ruolin, Sui Jingzhe, Qin Xue, Li Shan

Abstract excerpt

BACKGROUND: The base excision repair (BER) pathway removes DNA damage caused by ionizing radiation, reactive oxidative species and methylating agents. OGG1 and APE1 are two important genes in the BER pathway. Many epidemiological studies have evaluated the association between polymorphisms in the two BER genes (OGG1 Ser326Cys and APE1 Asp148Glu) and breast cancer risk. However, the results are inconsistent....

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Source

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Identifiers

PMID: 24893568
DOI: 10.1186/1746-1596-9-108
PMCID: PMC4064811

Genes

OGG1
APEX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Association between OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and breast cancer risk: a meta-analysis.PMID 24893568Read ↗

Impact of genetic polymorphisms in base excision repair genes on the risk of breast cancer in a Korean population.Semantic proximity Read ↗

The hOGG1 Ser326Cys polymorphism and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

Single nucleotide polymorphisms of DNA base-excision repair genes (APE1, OGG1 and XRCC1) associated with breast cancer risk in a Chinese population.Semantic proximity Read ↗

The effect of hOGG1 Ser326Cys polymorphism on cancer risk: evidence from a meta-analysis.Semantic proximity Read ↗

A systematic review and meta-analysis of the association between OGG1 Ser326Cys polymorphism and cancers.Semantic proximity Read ↗

Genetic polymorphisms in APE1 Asp148Glu(rs3136820) as a modifier of the background levels of abasic sites in human leukocytes derived from breast cancer patients and controls.Semantic proximity Read ↗

Impact of DNA polymorphisms in key DNA base excision repair proteins on cancer risk.Semantic proximity Read ↗

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Association of APEX1 and OGG1 gene polymorphisms with breast cancer risk among Han women in the Gansu Province of China.Semantic proximity Read ↗

Association between the OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and lung cancer risk: a meta-analysis.Semantic proximity Read ↗

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