Article
Impact of DNA polymorphisms in key DNA base excision repair proteins on cancer risk.
Human & experimental toxicology - 1 Oct 2012
Karahalil B, Bohr V A, Wilson D M
Abstract excerpt
Genetic variation in DNA repair genes can modulate DNA repair capacity and may be related to cancer risk. However, study findings have been inconsistent. Inheritance of variant DNA repair genes is believed to influence individual susceptibility to the development of environmental cancer. Reliable knowledge on which the base excision repair (BER) sequence variants are associated with cancer risk would help...
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