Association between polymorphisms in genes related to DNA base-excision repair with risk and prognosis of oropharyngeal squamous cell carcinoma.

doi:10.1007/s00432-016-2202-8

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Article

Association between polymorphisms in genes related to DNA base-excision repair with risk and prognosis of oropharyngeal squamous cell carcinoma.

Journal of cancer research and clinical oncology - 1 Sept 2016

Costa Ericka Francislaine Dias, Santos Erika Stocco, Liutti Vitor Teixeira, Leal Frederico, Santos Vivian Castro Antunes, Rinck-Junior José Augusto, Mariano Fernanda Viviane, Coutinho-Camillo Cláudia Malheiros, Altemani Albina, Lima Carmen Silvia Passos, Lourenço Gustavo Jacob

Abstract excerpt

PURPOSE: We examined the influence of OGG1 c.977C>G (rs1052133), APEX1 c.444T>G (rs1130409), XRCC1 c.-77T>C (rs3213245), c.580C>T (), () and () single-nucleotide polymorphisms (SNPs), involved in base-excision repair (BER) pathway, on oropharyngeal squamous cell carcinoma (OPSCC) risk and prognosis. METHODS: Aiming to identify the genotypes, DNA from 200 consecutive OPSCC...

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Share to Carcinoma, Squamous Cell
Share to DNA-(Apurinic or Apyrimidinic Site) Lyase
Share to DNA-Binding Proteins
Share to DNA Glycosylases
Share to DNA Repair
Share to Genetic Association Studies
Share to Oropharyngeal Neoplasms
Share to X-ray Repair Cross Complementing Protein 1

Source

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Identifiers

PMID: 27372710
DOI: 10.1007/s00432-016-2202-8

Genes

XRCC1
OGG1
APEX1

Variants

rs1052133
rs25489
rs3213245
rs1799782

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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