SNP-SNP interactions between DNA repair genes were associated with breast cancer risk in a Korean population.

doi:10.1002/cncr.26220

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SNP-SNP interactions between DNA repair genes were associated with breast cancer risk in a Korean population.

Cancer - 1 Feb 2012

Han Wonshik, Kim Kyoung-Yeon, Yang Song-Ju, Noh Dong-Young, Kang Daehee, Kwack KyuBum

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) in nucleotide excision repair (NER) pathway genes may modulate DNA repair capacity and increase susceptibility to breast cancer (BC). A case-control study was conducted by evaluating genes involved in DNA repair to identify polymorphisms associated with BC. METHODS: The 384 SNPs of 38 candidate genes were genotyped using the Illumina GoldenGate method. Genotypes...

Topics

Adult
Aged
Breast Neoplasms
Case-Control Studies
DNA
DNA Repair
DNA Repair Enzymes
DNA-Binding Proteins
Endonucleases
Female
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Humans

Male

Middle Aged

Polymerase Chain Reaction

Polymorphism, Single Nucleotide

Republic of Korea

Source

Open in PubMed

Identifiers

PMID: 21751184
DOI: 10.1002/cncr.26220

Genes

ERCC2
XPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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