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Article

Polymorphisms in three base excision repair genes and breast cancer risk in Thai women.

Breast cancer research and treatment - 1 Sept 2008

Sangrajrang Suleeporn, Schmezer Peter, Burkholder Iris, Waas Peter, Boffetta Paolo, Brennan Paul, Bartsch Helmut, Wiangnon Surapon, Popanda Odilia

Abstract excerpt

DNA repair plays an important role in tumor development. The base excision repair (BER) pathway mainly removes DNA damage caused by ionizing radiation and reactive oxidative species. Here, we examined possible associations between polymorphisms in three important BER genes (OGG1 Ser326Cys, APEX1 Asp148Glu, XRCC1 Arg194Trp, XRCC1 Arg280His, XRCC1 Arg399Gln) and breast cancer incidence in Thai women. The study...

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Identifiers

PMID: 17922186
DOI: 10.1007/s10549-007-9773-7

Genes

XRCC1
APEX1
OGG1
CGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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