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Article

Germline variations of apurinic/apyrimidinic endonuclease 1 (APEX1) detected in female breast cancer patients.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Ali Kashif, Mahjabeen Ishrat, Sabir Maimoona, Baig Ruqia Mehmood, Zafeer Maryam, Faheem Muhammad, Kayani Mahmood Akhtar

Abstract excerpt

Apurinic/apyrimidinic endonuclease 1 (APEX1) is a multifunctional protein which plays a central role in the BER pathway. APEX1 gene being highly polymorphic in cancer patients and has been indicated to have a contributive role in Apurinic/apyrimidinic (AP) site accumulation in DNA and consequently an increased risk of cancer development. In this case-control study, all exons of the APEX1 gene and its exon/intron...

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Identifiers

PMID: 25292033
DOI: 10.7314/apjcp.2014.15.18.7589

Genes

APEX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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